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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIG3
All Species:
10
Human Site:
Y279
Identified Species:
18.33
UniProt:
P49916
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49916
NP_002302.2
1009
112907
Y279
M
V
A
D
N
P
S
Y
N
T
K
T
Q
I
I
Chimpanzee
Pan troglodytes
XP_511409
922
102716
C249
L
F
S
R
I
F
N
C
N
P
D
D
M
A
R
Rhesus Macaque
Macaca mulatta
XP_001113780
1009
112805
Y279
M
V
A
D
N
P
S
Y
N
T
K
T
Q
I
I
Dog
Lupus familis
XP_548265
991
110592
Y280
M
V
A
E
N
P
S
Y
N
T
K
T
Q
I
I
Cat
Felis silvestris
Mouse
Mus musculus
P97386
1015
113000
K284
E
N
P
S
Y
N
T
K
T
Q
I
I
H
D
F
Rat
Rattus norvegicus
NP_001012011
943
105425
R269
D
C
L
L
R
E
F
R
K
L
C
A
M
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006215
902
101303
V229
L
P
G
I
I
K
I
V
Y
N
L
N
D
K
Q
Frog
Xenopus laevis
NP_001082183
988
110688
Q249
P
S
Y
N
S
K
T
Q
I
I
R
D
F
L
T
Zebra Danio
Brachydanio rerio
NP_001025345
752
84159
W79
D
I
T
E
L
E
G
W
E
E
L
Q
D
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650187
806
90830
K133
R
K
H
F
A
A
S
K
K
L
K
P
Q
K
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27474
773
86292
I100
T
G
R
T
E
G
K
I
K
E
D
L
R
A
K
Sea Urchin
Strong. purpuratus
XP_786357
875
97201
V202
G
H
H
A
K
T
K
V
V
A
A
Y
L
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P04819
755
84810
T82
S
G
E
E
E
Y
A
T
K
K
L
K
Q
T
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.1
97.7
89.4
N.A.
87.3
82.4
N.A.
N.A.
71.3
68.2
55.7
N.A.
34.9
N.A.
23.3
48.4
Protein Similarity:
100
91.1
98.8
92.2
N.A.
91.3
86.4
N.A.
N.A.
78.9
79.6
64.9
N.A.
48.1
N.A.
39.3
62.9
P-Site Identity:
100
6.6
100
93.3
N.A.
0
0
N.A.
N.A.
0
0
0
N.A.
20
N.A.
0
0
P-Site Similarity:
100
26.6
100
100
N.A.
6.6
6.6
N.A.
N.A.
6.6
33.3
20
N.A.
20
N.A.
6.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
24
8
8
8
8
0
0
8
8
8
0
16
16
% A
% Cys:
0
8
0
0
0
0
0
8
0
0
8
0
0
0
0
% C
% Asp:
16
0
0
16
0
0
0
0
0
0
16
16
16
8
8
% D
% Glu:
8
0
8
24
16
16
0
0
8
16
0
0
0
8
0
% E
% Phe:
0
8
0
8
0
8
8
0
0
0
0
0
8
0
8
% F
% Gly:
8
16
8
0
0
8
8
0
0
0
0
0
0
0
0
% G
% His:
0
8
16
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
8
0
8
16
0
8
8
8
8
8
8
0
24
24
% I
% Lys:
0
8
0
0
8
16
16
16
31
8
31
8
0
24
8
% K
% Leu:
16
0
8
8
8
0
0
0
0
16
24
8
8
8
0
% L
% Met:
24
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% M
% Asn:
0
8
0
8
24
8
8
0
31
8
0
8
0
0
0
% N
% Pro:
8
8
8
0
0
24
0
0
0
8
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
8
0
8
39
0
16
% Q
% Arg:
8
0
8
8
8
0
0
8
0
0
8
0
8
0
16
% R
% Ser:
8
8
8
8
8
0
31
0
0
0
0
0
0
0
0
% S
% Thr:
8
0
8
8
0
8
16
8
8
24
0
24
0
8
8
% T
% Val:
0
24
0
0
0
0
0
16
8
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
8
8
0
24
8
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _